logo nano spa 1

demo resto

  • Cabecera 1
    nanoscience and nanotechnology: small is different
  • Home
  • Advanced Fluorescence Nanoscopy
  • Publications

Publications

https://scholar.google.com/citations?user=yvIsuacAAAAJ&hl=es&oi=ao

  1. Exploring bacteria–surface interactions with a fluorescent membrane tension probe
    Carmen Gonzalez-Garcia, Daniel Ballesteros, Jaime J. Hernandez, Manuel Pazos, Isabel Rodríguez, Jose Requejo-Isidro, Cristina Flors, PNAS, 2025, 122, e2512977122V. Vadillo-Rodríguez, P. Pedraz, C. Flors, How much force is needed to kill a single bacterium?, Small 2025, 21, 24079902. 
  2. In Situ Single-Cell Bacterial Imaging Provides Mechanistic Insight into the Photodynamic Action of Photosensitizer-Loaded Hydrogels
    Ingrid V. Ortega, Tuğçe Şener Raman, Agnes Schulze, Cristina Flors
    ACS Applied Materials and Interfaces, 2024, 16, 5, 5677
  3. Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level
    Ingrid V. Ortega, Felipe Viela, Cristina Flors
    Open Biology, 2023, 13: 230020

  4. Real-Time Imaging of the Mechanobactericidal Action of Colloidal Nanomaterials and Nanostructured Topographies
    Felipe Viela, Ingrid V. Ortega, Jaime J. Hernández, Isabel Rodríguez, Sara Moreno-Da Silva, Alejandro López-Moreno, Emilio M. Pérez, Cristina Flors
    Small Science, 2023, 2300002

  5. Activatable iodinated BODIPYs for selective imaging and photodynamic disruption of amyloid structures in pathogenic bacterial biofilms
    6. J. Torra, T. Sawazaki, P. Bondia, S. Nonell, M. Kanai, Y. Sohma, C. Flors
    Sensors and Actuators B: Chemical, 2022, 371, 132475

  6. Versatile Near-Infrared Super-Resolution Imaging of Amyloid Fibrils with the Fluorogenic Probe CRANAD-2
    J. Torra, F. Viela, D. Megias, B. Sot, C. Flors
    Chemistry- A European Journal, 2022, 28, e202200026

  7. Min Oscillations as Real-time Reporter of Sublethal Effects in Photodynamic Treatment of Bacteria
    8. I. V. Ortega, J. Torra, C. Flors
    ACS Infectious Diseases, 2022, 8, 86

  8. Boosting the inactivation of bacterial biofilms by photodynamic targeting of matrix structures with Thioflavin T
    P. Bondia, C. Flors, J. Torra
    Chemical Communications, 2021,57, 8648

  9.  9-Aryl-phenalenones: Bioinspired thermally reversible photochromic compounds for photoswitching applications in the pico-to milliseconds range. R. Bresolí-Obach, W. A. Massad, A. Abudulimu, L. Lüer, C. Flors, J. G. Luis, L. I. Rosquete, Teresa A. Grillo, O. Anamimoghadam, G. Bucher, S. Nonell, Dyes and Pigments, 2021,186, 109060

  10. Long-term STED imaging of amyloid fibers with exchangeable Thioflavin T. J. Torra, P. Bondia, S. Gutierrez-Erlandsson, B. Sot, C. Flors, Nanoscale, 2020,12, 15050-15053

  11. Mechanically Induced Bacterial Death Imaged in Real Time: A Simultaneous Nanoindentation and Fluorescence Microscopy Study. A. del Valle, J. Torra, P. Bondia, C. M. Tone, P. Pedraz, V. Vadillo-Rodríguez, C. Flors, ACS Applied Materials & Interfaces 2020, 12 (28), 31235–31241

  12. Nanoscale view of amyloid photodynamic damage. P. Bondia, J. Torra, C. M. Tone, T. Sawazaki, A. del Valle, B. Sot, S. Nonell, M. Kanai, Y. Sohma, C. Flors, J. Am Chem. Soc. 2020, 142, 922

  13. Tailing miniSOG: structural bases of the complex photophysics of a flavin-binding singlet oxygen photosensitizing protein. Joaquim Torra, Céline Lafaye, Luca Signor, Sylvain Aumonier, Cristina Flors, Xiaokun Shu, Santi Nonell, Guillaume Gotthard, Antoine Royant, Sci. Rep. 2019, 9, 2428

  14. Linear assembly of lead bromide-based nanoparticles inside lead (II) polymers prepared by mixing the precursors of both the nanoparticle and the polymer. S. Gonzalez-Carrero, L. Bareño, E. Debroye, C. Martin, P. Bondia, C. Flors, R. E Galian, J. Hofkens, J. Pérez-Prieto, Chem. Commun. 2019, 55, 2968-2971

  15. Mechanics of Virus-like Particles Labeled with Green Fluorescent Protein. Johann Mertens, Patricia Bondia, CarolinaAllende-Ballestero, José L. Carrascosa, Cristina Flors, José R. Castón, Biophys. J. 2018, 115(8),1561

  16. Singlet Oxygen: Chemistry, Applications and Challenges Ahead. Cristina Flors, Axel G. Griesbeck, Georgios Vassilikogiannakis, ChemPhotoChem 2018, 2(7) 510

  17. Fluorescent Flavoprotein Heterodimers: Combining Photostability with Singlet Oxygen Generation. Alberto Rodríguez‐Pulido, Joaquim Torra, Sara H. Mejías, Aitziber L. Cortajarena, Rubén Ruiz‐González , Santi Nonell, Cristina Flors, ChemPhotoChem 2018, 2(7) 571

  18. Dominik Wöll and Cristina Flors, Super-resolution Fluorescence Imaging for Materials Science, Small Methods 2017, 1, 1700191 doi/10.1002/smtd.201700191/abstract

  19. Correlative Super-Resolution Fluorescence Imaging and Atomic Force Microscopy for the Characterization of Biological Samples, P. Bondia,S. Casado, C. Flors, Methods in Molecular Biology 2017, 1663, 105-113

  20. Super-resolution Fluorescence Imaging for Materials Science, D. Wöll, C. Flors, Small Methods 2017, 1(10), 1700191

  21. Hybrid nanoscopy of hybrid nanomaterials, P. Bondia, R. Jurado, S. Casado, J. M. Domínguez-Vera, N. Gálvez, C. Flors, Small 2017, 13(17), 1604128.

  22. Photoswitching-Enabled Contrast Enhancement in Light Sheet Fluorescence Microscopy, T. Vettenburg, A. Corral, A. Rodríguez-Pulido, C. Flors, J. Ripoll, ACS Photonics 2017, 4(3), 424-428

  23. Real-time imaging of photodynamic action in bacteria, A. Gollmer, A. Felgentraeger, T. Maisch, C. Flors, J. Biophoton. 2017, 10(2), 264-270

  24. Assessing the potential of photosensitizing flavoproteins as tags for correlative microscopy, A. Rodríguez-Pulido, A. L. Cortajarena, J. Torra, R. Ruiz-González, S. Nonell and C. Flors, Chem. Commun., 2016, 52, 8405-8408

  25. Apoferritin Fibers: a New Template for 1D Fluorescent Hybrid Nanostructures, R. Jurado, F. Castello, P. Bondia, S. Casado, C. Flors, R. Cuesta, J. M. Domínguez-Vera, Á. Orte and N. Gálvez, Nanoscale 2016, 8, 9648-9656

  26. Antibacterial Activity of DNA-Stabilized Silver Nanoclusters Tuned by Oligonucleotide Sequence, S. Javani, R. Lorca, A. Latorre, C. Flors, A. L. Cortajarena, and Á. Somoza, ACS Appl. Mater. Interfaces 2016, 8 (16), pp 10147–10154

  27. Biologically controlled synthesis and assembly of magnetite nanoparticles, M. Bennet, L. Bertinetti, R. K. Neely, A. Schertel, A. Körnig, C. Flors, F. D. Müller, D. Schüler, S. Klumpp, D. Faivre, Faraday Discuss 2015, 18, 71-83.

  28. β-Phenyl quenching of 9-phenylphenalenones: a novel photocyclisation reaction with biological implications, G. Bucher, R. Bresolí-Obach, C. Brosa, C. Flors, J. G. Luis, T. A. Grillo, S. Nonell, Phys. Chem. Chem. Phys. 2014,16, 18813-18820

  29. Correlative Atomic Force Microscopy and Localization-Based Super-Resolution Microscopy: Revealing Labelling and Image Reconstruction Artefacts, A. Monserrate, S. Casado, C. Flors, ChemPhysChem 2014, 5, 647–650

  30. Singlet Oxygen Generation by the Genetically Encoded Tag miniSOG, R. Ruiz-González, A. L. Cortajarena, S. H. Mejias, M. Agut, S. Nonell, C. Flors, J. Am. Chem. Soc., 2013, 135 (26), 9564–9567

  31. Super-resolution fluorescence imaging of directly labelled DNA: from microscopy standards to living cells, C. Flors, J. Microscopy 2013, 251, 1-4

  32. Naphthoxanthenyl, a New Stable Phenalenyl Type Radical Stabilized by Electronic Effects, O. Anamimoghadam, M. D. Symes, C. Busche, D.-L. Long, S. T. Caldwell, C. Flors, S. Nonell, L. Cronin, G. Bucher, Org. Lett., 2013, 15 (12), 2970–2973

  33. Single-molecule imaging at high hydrostatic pressure, H. Vass, S. L. Black, C. Flors, D. Lloyd, F. B. Ward, R. J. Allen, Appl. Phys. Lett. 2013, 102, 154103

  34. Fluorescent proteins as singlet oxygen photosensitizers: mechanistic studies in photodynamic inactivation of bacteria, R. Ruiz-González, J. H. White, A. L. Cortajarena, M. Agut, S. Nonell, C. Flors, Proc. SPIE 8596, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications V, 859609 (2013)

  35. A genetically-encoded photosensitiser demonstrates killing of bacteria by purely endogenous singlet oxygen, R. Ruiz-González, J. H. White, M. Agut, S. Nonell, C. Flors, Photochem. Photobiol. Sci., 2012,11, 1411-1413

  36. Reversible Fluorescence Photoswitching in DNA, D. A. Smith, P. Holliger, C. Flors, J. Phys. Chem. B, 2012, 116 (34), 10290–10293

  37. Super-resolution fluorescence microscopy as a tool to study the nanoscale organization of chromosomes, C. Flors, W. C. Earnshaw, Curr. Op. Chem. Biol, 2011, 15, 838–844

  38. FIT for Purpose: PNA-Based Probes Enable mRNA Imaging in Living Cells, J. Tilsner, C. Flors, ChemBioChem 2011, 12, 1007-9

  39. DNA and Chromatin Imaging with Super-Resolution Fluorescence Microscopy Based on Single-Molecule Localization, C. Flors, Biopolymers 2011, 95, 290-7

  40. Quantification of Photosensitized Singlet Oxygen Production by a Fluorescent Protein, X. Ragàs, L. P. Cooper, J. H. White, S. Nonell, C. Flors, ChemPhysChem 2011, 12, 161-5

  41. Singlet oxygen photosensitisation by GFP mutants: oxygen accessibility to the chromophore, A. Jiménez-Banzo, X. Ragàs, S. Abbruzzetti, C. Viappiani, B. Campanini, C. Flors, S. Nonell, Photochem. Photobiol. Sci., 2010,9, 1336-1341

  42. A super-resolution map of the vertebrate kinetochore, S. A. Ribeiro, P. Vagnarelli, Y. Dong, T. Hori, B. F. McEwen, T. Fukagawa, C. Flors, W. C. Earnshaw, PNAS 2010, 107, 10484–10489

  43. Photoswitching of monomeric and dimeric DNA-intercalating cyanine dyes for super-resolution microscopy applications, C. Flors, Photochem. Photobiol. Sci., 2010,9, 643-648

  44. Super-Resolution Imaging of DNA Labelled with Intercalating Dyes, C. Flors, C. N. J. Ravarani, D. T. F. Dryden, ChemPhysChem 2009, 10, 2201–2204

  45. Constitutively active RhoA inhibits proliferation by retarding G(1) to S phase cell cycle progression and impairing cytokinesis, P. Morin, C. Flors, M. F. Olson, Eur. J. Cell Biol 2009, 88, 495–507

  46. Nonlinear optical properties of photoswitchable fluorescent proteins, I. Asselberghs, C. Flors, E. De Meulenaere, B. Champagne, J. Vanderleyden, K. Clays, Proc. SPIE 7403, Nanobiosystems: Processing, Characterization, and Applications II, 74030P (2009)

  47. Second-Harmonic Generation in GFP-like Proteins, I. Asselberghs, C. Flors, L. Ferrighi, E. Botek, B. Champagne, H. Mizuno, R. Ando, A. Miyawaki, J. Hofkens, M. Van der Auweraer, K. Clays, J. Am. Chem. Soc., 2008, 130 (46), pp 15713–15719

  48. How is cis-trans isomerization controlled in Dronpa mutants? A replica exchange molecular dynamics study, S. L. C. Moors , S. Michielssens, C. Flors, P. Dedecker, J. Hofkens, A. Ceulemans, J. Chem. Theory Comput., 2008, 4 (6), pp 1012–1020

  49. Dark states in monomeric red fluorescent proteins studied by fluorescence correlation and single molecule spectroscopy, J. Hendrix, C. Flors, P. Dedecker, J. Hofkens, Y. Engelborghs, Biophys. J. 2008, 94, p4103–4113

  50. Singlet oxygen photosensitization by EGFP and its chromophore HBDI, A. Jiménez-Banzo, S. Nonell, J. Hofkens, C. Flors, Biophys. J. 2008, 94, 168–172

  51. Subdiffraction imaging through the selective donut-mode depletion of thermally stable photoswitchable fluorophores: Numerical analysis and application to the fluorescent protein Dronpa, P. Dedecker , J. Hotta ,C. Flors, M. Sliwa ,H. Uji-i ,M. B. J. Roeffaers, R. Ando, H. Mizuno, A. Miyawaki, J. Hofkens, J. Am. Chem. Soc., 2007, 129 (51), pp 16132–16141

  52. A stroboscopic approach for fast photoactivation-localization microscopy with Dronpa mutants, C. Flors, J. Hotta, H. Uji-i ,P. Dedecker, R. Ando, H. Mizuno, A. Miyawaki , J. Hofkens, J. Am. Chem. Soc., 2007, 129 (45), pp 13970–13977

  53. 3D nanoscopy: Bringing biological nanostructures into sharp focus, P. Dedecker, C. Flors, J. Hotta, H. Uji-i, J. Hofkens, Angewandte Chem. Int. Ed. 2007, 46, 8330–8332

  54. Single perylene diimide dendrimers as single-photon sources, M. Sliwa, C. Flors, I. Oesterling, J. Hotta, K. Müllen, F. C. De Schryver, J. Hofkens, J. Phys.: Condens. Matter 19 445004

  55. Highlighted generation of fluorescence signals using simultaneous two-color irradiation on Dronpa mutants, R. Ando, C. Flors, H. Mizuno, J. Hofkens, A. Miyawaki, Biophys. J. 2007, 92, L97–L99

  56. Ultrafast excited-state dynamics of the photoswitchable protein dronpa, E. Fron, C. Flors, G. Schweitzer, S. Habuchi, H. Mizuno, R. Ando, F. C. De Schryver, A. Miyawaki, J. Hofkens, J. Am. Chem. Soc., 2007, 129 (16), pp 4870–4871

  57. Energy and electron transfer in ethynylene bridged perylene diimide multichromophores, C. Flors ,I. Oesterling, T. Schnitzler, E. Fron, G. Schweitzer, M. Sliwa, A. Herrmann, M. van der Auweraer, F. C. de Schryver, K. Müllen, J. Hofkens, J. Phys. Chem. C, 2007, 111 (12), pp 4861–4870

  58. Photo-induced protonation/deprotonation in the GFP-like fluorescent protein Dronpa: mechanism responsible for the reversible photoswitching, S. Habuchi, P. Dedecker, J. Hotta, C. Flors, R. Ando, H. Mizuno, A. Miyawaki, J. Hofkens, Photochem. Photobiol. Sci., 2006,5, 567-576

  59. Photoconversion in the red fluorescent protein from the sea anemone Entacmaea quadricolor: Is cis-trans isomerization involved?, D. Loos , S. Habuchi, C. Flors, J. Hotta, J. Wiedenmann, G. U. Nienhaus, J. Hofkens, J. Am. Chem. Soc., 2006, 128 (19), pp 6270–6271

  60. Solvent and pH dependent fluorescent properties of a dimethylaminostyryl borondipyrromethene dye in solution, M. Baruah, W. Qin, C. Flors , J. Hofkens, R. A. L. Vallée , D. Beljonne , M. Van der Auweraer, W. M. De Borggraeve, N. Boens, J. Phys. Chem. A, 2006, 110 (18), pp 5998–6009

  61. Light and singlet oxygen in plant defense against pathogens: Phototoxic phenalenone phytoalexins, C. Flors, S. Nonell, Acc. Chem. Res., 2006, 39 (5), pp 293–300

  62. Imaging the production of singlet oxygen in vivo using a new fluorescent sensor, Singlet Oxygen Sensor Green (R), C. Flors, M. J Fryer, J. Waring, B. Reeder, U. Bechtold, P. M. Mullineaux, S. Nonell, M. T. Wilson, N. R Baker, J. Exp. Bot. (2006) 57 (8): 1725-1734.

  63. Phototoxic phytoalexins. Processes that compete with the photosensitized production of singlet oxygen by 9-phenylphenalenones, C. Flors, P. R. Ogilby, J. G. Luis, T. A. Grillo, L. R. Izquierdo, P-L Gentili, L. Bussotti, S. Nonell, Photochem. Photobiol. 2006, 82, 95–103

  64. Photochemistry of phytoalexins containing phenalenone-like chromophores: Photophysics and singlet oxygen photosensitizing properties of the plant oxoaporphine alkaloid oxoglaucine, C. Flors, C. Prat, R. Suau, F. Nájera, S. Nonell, Photochem. Photobiol. 2005, 81, 120-124

  65. Light- and singlet oxygen-mediated antifungal activity of phenylphenalenone phytoalexins, A. Lazzaro, M. Corominas, C. Martí, C. Flors, L. R. Izquierdo, T. A. Grillo, J. G. Luis, S. Nonell, Photochem. Photobiol. Sci., 2004,3, 706-710

  66. Radical species derived from phenalenone: characterization and role of upper excited states, C. Flors, S. Nonell, J. Photochem. Photobiol. A. Chem. 2004, 163, 9-12

  67. On the phosphorescence of 1H-phenalen-1-one, C. Flors, S. Nonell, Helv. Chim. Acta 2001, 84, 2533–2539