SINTEF and our ecosystem for innovation: “From the lab to the market: lessons learned from nanomedicine translation at SINTEF”

Abstract:

During this presentation, SINTEF in general and in more detail the Department of Biotechnology and Nanomedicine will be presented, followed by examples and lessons learned in the field of nanomedicine translation from idea to the market and clinic. Important strategic decisions made at SINTEF contributed to our success in innovation and translation, e.g. building multidisciplinary expertise along the whole value chain from drug discovery to preclinical characterization and targeted investment into necessary infrastructure. The story of our poly (alkyl cyanoacrylate) based drug delivery platform, starting in 2012 with an idea, forming a spin-off company in 2022, and just a few weeks ago finally receiving the approval of the clinical trial application (CTA) for the Phase 1 first-in-human trial, will be used as the main example, a red thread, but also other examples will illustrate the lessons learned, e.g. the importance of formulation and characterization work developed hand-in-hand.

Short bio:

Ruth Schmid is a retired, former Vice President Marketing at SINTEF Industry in Trondheim, Norway with special responsibility for the area of medical technology, including nanomedicine. She is a Swiss citizen living in Norway since 1979. She gained her Diploma (1975) and PhD (1979) in Natural Sciences at ETH Zürich, Switzerland. She is a member of ACS, CRS (Past-President), and the European Technology Platform on Nanomedicine (Past-Chair). She is married and has three adult children.

Research activities include the preparation and characterization of micro- and nanoparticles by various technologies and from a wide variety of materials, as well as the surface modification of polymers and polymer particles to introduce tailor-made properties, with special focus on applied research and product orientated solutions. Beyond a special interest in nanomedicine, application of encapsulation technologies and controlled release in various industrial segments, e.g. medicine, animal health, cosmetics, household and body care products, food and beverages, agriculture are of interest. Scientific contributions with high translational impact are key contributions to the development of the Dynabeads™ (Thermo Fisher) and the idea for and development of a poly (alkyl cyanoacrylate) based drug delivery platform, which is the basis of NaDeNo Nanoscience, a late-stage preclinical biotechnology company, with a first lead candidate for local treatment of peritoneal micrometastases from ovarian cancer.

She describes herself as an inclusive and motivating leader and mentor, contributing to solving scientific and technological problems by nurturing interdisciplinary research collaborations and focusing on translation from bench to market/clinic, as well as a strategic and creative person, driven by the motto “interfaces are a breeding ground for life, creativity and interaction”.

This seminar is hosted by Mario Martinez Mingo (This email address is being protected from spambots. You need JavaScript enabled to view it.) 

To get an assistance certificate for this seminar, register now and sign the assistance form during the seminar: https://docs.google.com/forms/d/e/1FAIpQLSfZnYbqOf3qR6jvPt_sZiT71r3EiNSGqKOBvyRswsu2gpJJvQ/viewform?usp=publish-editor